I think you can use your vote trying to prevent the pest, since fighting collera is easier. If you think there is no difference what so ever between having a right wing government (democrats) versus an authoritarian (republicans) I would argue that both parties dont care about average people, but with the right wing government in place you have It a bit easier fighting your battles in direct action etc. You bring positive change via Direct action and community building, with your vote you can influence the circumstances a little bit and how hard the fight will be. But There will be a fight no matter who is in charge. But do you want to play this on hard or nightmare mode?