• 4 Posts
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Joined 2 years ago
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Cake day: June 30th, 2023

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  • At the end of the day, most of what people care about isn’t age, it’s cognitive function (though age itself is important; why care about the America of 2040 if you won’t live to see it).

    Many of these people in power would fight age limits, but they are usually so sure of their abilities, that they may not fight cognitive tests with published results.

    For example, if you give someone a Montreal cognitive assessment, and their reaction to it is:

    Yes, the first few questions are easy, but I’ll bet you couldn’t even answer the last five questions. I’ll bet you couldn’t, they get very hard, the last five questions

    And those last 5 questions are:

    What month are we in? What year are we in? What day of the week is it? Where are you right now? What city are you in?

    You might think that person shouldn’t be in charge of the country.

    Oops.








  • All the concern about this dye is based on a 1990 study where they fed rats 0.5%, 1%, or 4% of their diet by mass with the dye. Only the group with 4% of their diet had an effect on thyroid stimulating hormone, and follow on effects on t3 and t4. This increased stimulation of the thyroid is what they hypothesized is responsible for potential tumor growth. That dose is ~5,000-15,000 times higher than a regular diet. Increasing sugar or alcohol or literally anything else in your diet by that amount will have dire consequences.

    Furthermore, the authors mention that a 100x dose human trial had increased TSH, but without changes to t3 or t4. This (and other factors they bring up in the paper) show that humans don’t respond like rats, so these rat studies can’t really be applied to humans. Even a massive overdose wouldn’t have the same potential for causing cancer in human as it does in rats.

    All that said, there’s no benefits to the consumer to have food that’s just more red. Banning red 3 isn’t going to make manufacturers stop dyeing food red, it’s going to make them switch dyes, which might not be able net positive.

    The FDA’s notice even says this:

    two studies that showed cancer in laboratory male rats exposed to high levels of FD&C Red No. 3 due to a rat specific hormonal mechanism. The way that FD&C Red No. 3 causes cancer in male rats does not occur in humans. Relevant exposure levels to FD&C Red No. 3 for humans are typically much lower than those that cause the effects shown in male rats. Studies in other animals and in humans did not show these effects; claims that the use of FD&C Red No. 3 in food and in ingested drugs puts people at risk are not supported by the available scientific information.

    They mention that they are forced to ban it due to a technicality of the law:

    The Delaney Clause, enacted in 1960 as part of the Color Additives Amendment to the FD&C Act, prohibits FDA authorization of a food additive or color additive if it has been found to induce cancer in humans or animals.

    So even if we know for sure that a substance is fine for humans, if there’s any animal that could be given cancer by ingestion of any dose, it legally should be banned.

    For example, if you did a study where you fed dogs chocolate for a year, and they developed liver cancer due to the constant poisoning, you could petition to have chocolate banned as a food edditive.



  • I’m in the midst of planning out some built-ins. When looking for inspiration, it is so annoying how many videos/blog posts, etc, on creating built-ins start with “buy IKEA cabinetry”.

    If you are buying cabinets, you aren’t building cabinets. Yeah, there’s assembly involved, but watching someone buy a cabinet, and then just paint it and put different hardware on it doesn’t help me at all.

    For example, I’m trying to figure out the right way to have the cabinet doors interface with adjacent window trim. I.e, do I cut the trim to fit the cabinet doors, or do I alter the cabinet doors to fit the windows trim.

    The “ikea cabinet” people can’t have these choices cause it’s not possible to alter them since they are built of chipboard.