In which cases does SRY not mean male?

Khelif confirmed she has the SRY gene

The quotes that came directly from Khelif mean that Khelif is male. You’re ignoring the quote that came directly from Khelif admitting to having an SRY gene.

That doesn’t refute Khelif being male. That simply means Khelif was incorrectly AFAB, because again, Khelif is self-admittedly male.

No comment on the people in the list. Because it was written by Drew DeVault though, you should assume that it’s heavily slanted and that its purpose is to benefit Drew DeVault.

Directly in the sense that it was something Khelif directly said. There were leaked sex tests before this that people dismissed as rumor.

These statements came directly from Khelif and can only be interpreted as Khelif being male. The statements cannot be interpreted as Khelif being female.

The medical side is what makes the statement true.

SRY = male except in very rare cases. Khelif is not one of those cases, and thus is male.

Drew DeVault is a weird little pedophile

https://dmpwn.info/

Don’t engage with him at all

Khelif confirmed she has the SRY gene

I have taken hormone treatments to lower my testosterone levels

Swyer syndrome would lead to low testosterone. There’s no other possibility for Khelif being female

I am a girl. I was raised as a girl, I grew up as a girl, the people in my village have always known me as a girl," Khelif said.

Incorrectly AFAB.

This community is for critical analysis, but that does not include “nuh uh!”. What alternative explanation can you offer?

Imane Khelif is not trans. It is true though that Khelif has directly admitted to being male and was incorrectly assigned female at birth due to having a DSD

https://www.lemonde.fr/en/sports/article/2026/02/05/boxer-imane-khelif-reveals-she-took-hormone-treatment-before-paris-olympics_6750171_9.html

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2851743

Given these factors—from absent temporal sequencing and unmeasured baseline severity to exposure misclassification and dataset limitations—I do not believe that the study can substantiate the suggestion that PBs confer MH benefits or justify their further implication that earlier hormonal intervention may be beneficial.

58% of the group didn’t respond. That creates a huge selection bias that doesn’t make it worth getting into the study’s other flaws.

Tautological definitions clarify nothing.

What matters is what someone means with a word. If someone says they’re straight, what do they mean?

What do you do when the ideas are “sex-based bathrooms and nothing else will do”? Yawning seems unlikely to make any progress.

Where do you see meaningful progress coming from? To read into your response a bit via “I would be surprised if they’re substantially wrong”, are you saying that sex is binary and immutable in humans? That’s a falsifiable claim, and progress could be made by either proving or disproving it.

they’re too busy policing women’s bodies

I think the standard answer is “Men should just respect women’s spaces”. What do you tell someone that agrees with “The biggest threat to women’s safety is men” and also believes sex is real, i.e. a TERF? It doesn’t seem like a lot of progress will be made with “The biggest threat to your safety is just a distraction”

Posted for critical analysis.

Are the models correct, or biased? How does that reflect their training data and how people use them? What makes those discussions tired?

The biggest threat to women’s safety (and perception of it) is men

Interesting, that’s exactly what TERFs say

Completely unscientific, but here’s what duck.ai says

GPT-5.6 Luna

The community note is substantially correct, and the response is not a sound biological rebuttal.

The first tweet gives a basically standard account of human biological sex: females are organized around the production of ova, while males are organized around the production of sperm. A more precise formulation would be:

In humans, female refers to the reproductive organization or developmental pathway centered on ova production, whether or not an individual currently produces viable ova.

That qualification matters because children, postmenopausal women, infertile women, people with certain disorders of sexual development, and people whose reproductive organs have been removed may not actually produce eggs. Their sex classification is based on the reproductive system they developed—or were organized—to have, not on current fertility.

The claim “I just described every female on earth” is too broad if intended across all animals, because reproductive systems and sex classifications vary among species. But for humans, it is a reasonable simplified description.

“Being female means having the brain of a woman” is not an established biological definition. Human brains show some average sex-associated differences, but those differences are generally small, highly overlapping, affected by development and environment, and not a reliable binary test for whether someone is biologically male or female. There is no medically accepted “female brain” criterion that defines sex.

There is also a category distinction:

• Female/male ordinarily refer to biological sex.
• Woman/man can refer either to adult sex categories or, in contemporary gender terminology, to gender identity.
• A person’s gender identity is not determined by a measurable “brain of a woman” classification.

So the best assessment is: the response is biologically unsupported; the community note correctly identifies the relevant scientific distinction; and the original tweet is broadly right about humans but could be worded more precisely.

Gemma 4 (2nd opinion)

This dispute centers on the distinction between biological sex and gender identity. The original tweet defines female based on the biological principle of anisogamy, where sex is determined by the type of gamete an organism is organized to produce—eggs for females and sperm for males. This is the standard scientific definition used in biology to categorize sex across species, regardless of whether an individual’s reproductive system is functional or has been altered.

The response shifts the definition from biological sex to a neurological or psychological framework, claiming that being female is defined by having the brain of a woman. This perspective aligns more with concepts of gender identity or “brain sex” rather than biological classification.

The community note functions as a factual correction of the response’s biological claim. It clarifies that biological sex is defined by reproductive anatomy and gamete production, not by brain structure. It further notes that differences in brain structure between males and females are small and overlapping, meaning they are not distinct enough to serve as a primary defining characteristic for biological sex.

Ultimately, the dispute is a clash of frameworks. The first tweet and the community note operate within a biological framework, while the response operates within a neurological or identity-based framework. The community note concludes that the response is factually incorrect because it attempts to use brain structure as the defining metric for a biological category.

Nathan Cofnas is the one that broke the story about Jason Arday

https://xcancel.com/nathancofnas/status/2079542388389724403

The article he’s talking about has a section about DSDs that I think also covers what his response would be to sterility

However, the existence of such conditions does not undermine the binary nature of sex, because the sex binary does not entail that every individual can be unambiguously categorized as male or female. Rather, the claim is that in anisogamous organisms there are only two gamete types, sperm and ova, and thus only two sexes. Sexual ambiguity is not a third or intermediate sex because developmental variation does not correspond to producing new gamete types.

I think you’re right that people are talking past each other on this. Biologists use gametes because they care about defining sex in a meaningful way when talking about both humans and crabs. We don’t care about crabs using the bathroom though.

IMO the blame is on Cambridge. They had the chance to quietly let him go when it was clear he was both a plagiarist and a fantastic liar.